What is RAD-140 (Testolone)? A Comprehensive Guide

Bay Drift
2 days ago
2 min read

What is RAD-140 (Testolone)? A Comprehensive Guide

1. What is It?

RAD-140, also known as Testolone, is a non-steroidal compound belonging to the Selective Androgen Receptor Modulator (SARM) class. It binds to androgen receptors with high affinity, while showing minimal effects on tissues like the prostate and hair follicles. It was developed for research purposes and is not approved for clinical use.

2. Key Benefits:

✔ Testosterone-like Anabolic Effect: Potentially as strong as 90% of traditional steroids.
✔ Lean Muscle Mass Gain: Can lead to 4-6 kg (9-13 lbs) of lean mass in 8 weeks.
✔ Strength Increase: May result in a 15-20% rise in 1-rep max (1RM).
✔ Increases Bone Density: Shows promise in osteoporosis research.
✔ Neuroprotective Effects: Being investigated for use in Alzheimer's research.
✔ No Androgenic Effect on Prostate: Less risk of prostate enlargement compared to anabolic steroids.

3. Combinations:

MK-677: 10-25mg/day (for synergy in increasing IGF-1).
LGD-4033: 5-10mg/day (for combined muscle mass enhancement).
Testosterone Base: 150-200mg/week (for protection against hypogonadism and to maintain baseline function).
Cardarine (GW-501516): 10-20mg/day (to stack for fat loss).

4. Pharmacokinetics:

Half-life: 20-24 hours.
Full Elimination from Body: 5-7 days.
Dosing Frequency: Once per day (in the morning).
Optimal Cycle Duration: 8-12 weeks.
Onset of Effects: 10-14 days.

5. Sample Cycle Protocol:

Week 1-12:
- RAD-140: 10-20mg/day (morning)
- NAC: 600mg/day (for liver protection)
- D3+K2: 5000IU/100mcg (for bone health)
PCT (Post Cycle Therapy - Week 13-16):
- Enclomiphene: 12.5mg/day
- Nolvadex: 10mg/day

6. Critical Warnings:

⚠ Testosterone Suppression: Dose-dependent suppression of 40-80% is common.
⚠ HDL Decrease: Can cause a drop of 15-20 points in "good" cholesterol.
⚠ Elevated Liver Enzymes: ALT/AST levels can increase 2-3 times.
⚠ Androgenic Alopecia: Possible if there is a genetic predisposition to hair loss.

7. Contraindications:

❌ Individuals under 18 years old.
❌ History of liver disease.
❌ History of hormone-sensitive cancers.
❌ Pregnancy/Breastfeeding.

Conclusion:

RAD-140 is a potent SARM developed as an alternative to traditional steroids. Preclinical studies in 2023 show promise for its potential in treating breast cancer. However, it should be used with caution as long-term safety data in humans is not yet available.

Note: RAD-140 is banned by WADA and most sports federations. Post-cycle testosterone levels typically return to normal within 4-12 weeks. A lipid panel and liver function tests are essential before use.