What is YK-11? A Comprehensive Guide

Bay Drift
May 29
2 min read

What is YK-11? A Comprehensive Guide

1. What is It?

YK-11 is a non-steroidal compound that combines the properties of a myostatin inhibitor and a selective androgen receptor modulator (SARM). It triggers muscle growth by increasing Follistatin production and directly binds to androgen receptors.

2. Key Benefits:

✔ Myostatin Inhibition: Removes the natural limit on muscle growth.
✔ Rapid Muscle Mass Gain: Potential for 5-8 kg (11-17 lbs) in 8 weeks.
✔ Increases Bone Density: Contributes to stronger bones.
✔ Strength Increase: Can lead to a 20-30% rise in 1-rep max (1RM).
✔ Supports Collagen Synthesis: Beneficial for joint health.
✔ Accelerates Fat Loss: Enhances metabolic rate.

3. Combinations:

Testosterone Base (Enanthate/Propionate): 300-500mg/week (for foundational androgenic support).
MK-677: 20-25mg/day (for IGF-1 and Follistatin synergy).
RAD-140: 10-20mg/day (a SARM + YK-11 stack for enhanced effects).
HCG: 500IU/week (to prevent testicular atrophy).

4. Pharmacokinetics:

Half-life: 6-8 hours.
Full Elimination from Body: 24-48 hours.
Dosing Frequency: 2-3 doses per day (every 8 hours).
Optimal Cycle Duration: 6-8 weeks.
Onset of Effects: 7-10 days.

5. Sample 8-Week Cycle Protocol:

Week 1-8:
- YK-11: 10-20mg/day (morning/evening)
- Testosterone Enanthate: 400mg/week
- TUDCA: 500mg/day (for liver protection)
PCT (Post Cycle Therapy - Week 9-12):
- HCG: 1500IU/week
- Clomid: 50mg/day
- Nolvadex: 20mg/day

6. Critical Warnings:

⚠ Liver Toxicity: ALT/AST levels can increase 3-5 times.
⚠ Testosterone Suppression: Significant suppression of 70-90% is common.
⚠ HDL Decrease: Can cause a drop of 20-30 points in "good" cholesterol.
⚠ Joint Pain: Potentially linked to myostatin inhibition.

7. Contraindications:

❌ Under 18 years old: Risk of epiphyseal plate closure.
❌ Liver disease: Pre-existing conditions are exacerbated.
❌ History of prostate enlargement: Can worsen the condition.
❌ Pregnancy/Breastfeeding: Unknown effects on fetal/infant development.

Conclusion:

YK-11 is a nuclear-level compound developed primarily for professional bodybuilders. While preclinical studies in 2023 showed promise for treating muscular dystrophy, there is no long-term safety data in humans.

Note: YK-11 is banned by WADA. Before use, liver function tests, a lipid panel, and an EKG are essential. It must not be used without a proper PCT plan.